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KMID : 1190620070030010019
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Journal of the Korean Wound Care Society
2007 Volume.3 No. 1 p.19 ~ p.23
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Microbiology in Diabetic Foot Patients in Korea
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Han Seung-Kyu
Lee Byung-Il
Kim Woo-Kyung
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Abstract
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This study was carried out to determine the common microorganisms of diabetic foot infection in Korea and antimicrobial sensitivity pattern to enhance possible empiric treatment. The specimens were obtained from wounds of 207 cases of diabetic foot ulcer, and the bacteriological isolation and antimicrobial susceptibility tests of the isolates were carried out by standard microbiological methods. Staphylococcus aureus was the most common isolate, being recovered from 46.2% of total bacterial isolated cases. Among gram-negative organisms, Pseudomonas aeruginosa was the most common. Gram-positive organisms showed significant susceptibility to clindamycin, trimethoprim/ sulfamethoxazole, and levofloxacin, besides vancomycin. Cefoperazone, piperacillin/tazobactam, and amikacin in addition to imipenem were the most effective agents against gram-negative organisms. Diabetic foot infection requires use of combined antimicrobial therapy for initial management. Our results indicate that the most effective antibiotic combination for diabetic foot infection of Korean patients is clindamycin plus cefoperazone. (J Korean Wound Care Soc 2007;3:19-23)
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KEYWORD
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Diabetic foot, Microorganism, Korea
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